SLE affects not only the joints, but also other organs like skin, kidneys, nervous systems, blood etc. The disease is seen more common in females of child bearing age group. The disease is precipitated by excess exposure to sunlight. It is diagnosed by means of simple blood tests. Sometimes the diagnosis and management might need kidney, skin or nerve biopsies or imaging modalities as MRI. The disease is treated by medicines such as Hydroxy Chloroquine, regulated use of corticosteroids or immunosuppressants as Cyclophosphamide and Mycophenolate Mofetil.