Ankylosing Spondylitis
Ankylosing Spondylitis (AS) is a prevalent inflammatory rheumatic disease, most commonly affecting young males but also impacting females. This condition primarily targets the spine, hips, and shoulders, though any joint can be involved. AS causes significant pain and stiffness, and, if untreated, can lead to the fusion of the spine and other joints. It has a genetic link, particularly associated with the HLA B27 gene. Effective management involves a combination of anti-inflammatory medications, disease-modifying anti-rheumatic drugs, and biological therapies to alleviate symptoms and prevent progression.
